3,4 DIHYDRO-2H-PYRROLO[1,2-a]PYRAZIN-1-ONE DERIVAT

专利名称：3,4 DIHYDRO-2H-PYRROLO[1,2-a]PYRAZIN-1-ONE DERIVATIVES

发明人：MIRIZZI, Danilo,CERVI, Giovanni,D'ANELLO,

Matteo,PAPEO, Gianluca MarianoEnrico,FERGUSON, Ron,CASUSCELLI,Francesco

申请号：EP09783126.7申请日：20090917公开号：EP2376492A1公开日：20111019

摘要：Compounds which are 4,7-disubstituted derivatives of3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one compounds, or pharmaceutically acceptable salts thereof,their preparation process and pharmaceutical compositions comprising them aredisclosed; these compounds are useful in the treatment of diseases caused by and/orassociated with an altered protein kinase activity such as cancer, viral infection, preventionof AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmuneand neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesisconditions for preparing the compounds of the invention and chemical librariescomprising a plurality of them.

申请人：Nerviano Medical Sciences S.r.l.

地址：11 Viale Pasteur, 10 P.O. Box 11 20014 Nerviano (MI) IT

国籍：IT

更多信息请下载全文后查看